That buttery rich flavor that so many people love on their popcorn may
harm more than just your waistline. The chemical that provides that
butter taste has now been associated with a buildup of the brain
proteins involved in Alzheimer's disease.
The research, conducted at the University of Minnesota in
Minneapolis, analyzed the ingredient diacetyl (DA) and its effects in a
laboratory study. First, when its internal structure was explored, the
team discovered that DA bears a close resemblance to the matter within
the brain that creates beta-amyloid proteins. These abnormal proteins
bunch up into masses of plaque, which are a known hallmark of
Alzheimer's disease in the brain.
The scientists then set up conditions in test tubes placing
DA on nerve cells that were grown for the experiment. The DA behaved
just as beta-amyloid proteins do, by massing together and causing a
misfolding of amyloid, thereby creating lumps of plaque. They also
damaged the nerve cells that were hosting them.
Now, you might wonder just how they could surface in the
brain when they should just make their way through the gastrointestinal
tract. The problem lies in the fact that DA enters the bloodstream as
the food is digested and can travel up to the brain. And in even low
concentrations, the chemical has the ability to cross the blood-brain
barrier that is meant to protect the brain from many potentially harmful
elements. Once there, DA hinders our ability to clear beta amyloid out
of the brain, which is how deposits end up remaining.
Natural DA is found in dairy products, including butter,
fruit, and fermented products such as wine and beer. Concentrated
synthetic DA, however, is what is used as flavoring in processed foods.
Since it is considered "safe" by the FDA, it does not have to be listed
by name on the label. Instead, you will usually find it listed as
"butter flavor" or some similar wording.
This is not the first time DA has been found to be an
unhealthy product. Several studies over the past few years have found
that this substance may be responsible for respiratory conditions in
those who inhale it. While this wouldn't affect the average consumer of
products containing DA, it is quite problematic for those who work in
the factories in which microwave popcorn and other artificially-flavored
food items are produced.
And you may not be safe from the stuff even if you are not a
big fan of butter-flavored microwave popcorn because that's far from
the only edible product in which DA can be found. The whole range of
butter substitute products, some types of candy, and lots of packaged
baked goods obtain their buttery smell and flavor through the use of DA.
Even Fluffy is at risk since some pet food manufacturers include DA as
an ingredient, presumably to make the food a little more palatable for
finicky animals. But back to humans! Other studies have discovered an
association between diet and the development of dementia or Alzheimer's
disease. Not to say that it is the sole cause, but it definitely appears
to have a negative effect. That said, it is important to consider not
only what not to eat, such as additives and chemicals including DA, but
also what may provide us with a little protection. A 2010 study that
took place at Columbia University in New York linked a Mediterranean-style diet
with lower rates of Alzheimer's disease. Those whose food consumption
focuses heavily on olive oil-based salad dressing, nuts, fish, tomatoes,
poultry, broccoli, fruits, and dark and green leafy vegetables and less
on red meat, organ meat, and high-fat dairy products were 40 percent
less likely to develop Alzheimer's than those following a more typical
American diet.
Exercise too is key in helping to prevent Alzheimer's
disease. Research has shown that giving the body regular workouts can
aid in staving off forms of dementia as well as many other conditions.
So although nothing in life comes with a guarantee, it would seem to be
in the best interest of our brains and our health in general if we
skipped over the fake-buttered popcorn, not to mention those "heart
healthy" fake margarines, and chose a more natural, nutritious snack
during television time. Or, better yet, shelve the viewing for later and
use the time to take a brisk walk or do a little stretching and toning.
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